Posted by ImproveCareNow™ on July 01, 2014
Forrest CB, Crandall WV, Bailey LC, Zhang P, Joffe MM, Colletti RB et al. Effectiveness of anti-TNF for Crohn’s disease: research in a pediatric learning health system. Pediatrics 2014; 134:37-44
ImproveCareNow (ICN) is the largest pediatric learning health system in the nation and started as a quality improvement collaborative. To test the feasibility and validity of using ICN data for clinical research, we evaluated the effectiveness of anti-tumor necrosis factor-α (anti-TNFα) agents in the management of pediatric Crohn disease (CD).