Singer AA, Gadepalli SK, Eder SJ, Adler J (2016). Fistulizing Crohn's Disease Presenting After Surgery on a Perianal Lesion.  Pediatrics 137(3).

Perianal skin lesions, such as skin tags, can be an early presenting sign of Crohn’s disease.  Surgical intervention on these lesions may increase the risk of fistula development and lead to worse outcomes.  This case series examined 8 patients who underwent surgical intervention on what appeared to be benign perianal skin lesions, only to reveal fistulas leading to the diagnosis of Crohn’s disease.

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