Primary Investigator: Malika Goel - UCSF Benioff Children's Hospitals
Hypothesis:
Given genetic and environmental differences, the timing and likelihood of biologic initiation, specific biologics used and the response to IBD treatment will be different in Asian patients as compared to African American / Black patients and White patients.
Specific Aims:
Aim 1) To compare the patterns and treatment variations in biologic therapy use, including a) the time and likelihood of the first biologic initiated within one year of disease diagnosis; b) type of biologic initiated within one year of disease diagnosis; c) changes in biologic treatment, if any, among Asian patients compared with African American/ Black patients and White patients within the one year of disease diagnosis.
Aim 2) To compare the differences in time to change to the second or third biologic among Asian patients compared with African American/Black patients and White patients within the one year of disease diagnosis.
Aim 3) To evaluate differences in remission rates achieved on First biologic therapy initiated between Asian patients compared with African American/Black patients and White patients within one year of disease diagnosis.