Ramsey L, Mizuno T, Vinks A, Margolis PA. Learning health systems as facilitators of precision medicine.  Clinical Pharmacology & Therapeutics 2017; 101(3): 359-367

The concept of the learning health system offers promise to facilitate personalized medicine. In children, serious illness is uncommon, so generating and applying new knowledge therefore requires networks of institutions. To illustrate the concept of the Learning Health System, we describe the example of the ImproveCareNow Network. We then use a network case study to illustrate how the concept of precision medicine can be achieved through a Learning Health System in a real-world clinical environment.

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