Specific Aims:
We aim to first determine the disease characteristics and other defining features at diagnosis among a large, multi-center population of pediatric patients with IBDU. We will then evaluate the frequency of diagnostic reclassification to Crohn’s disease or ulcerative colitis over time and assess for characteristics that predict a change in diagnosis. We will evaluate at extent of disease, gender, race, age, anthropometric data, lab data (hematocrit, albumin), and physician global assessment as possible predictors of change in diagnosis. Other secondary outcomes will include change in extent of disease, need for surgery, development of complications (fistula, growth failure, etc).
Study Period: September 2018-August 2023
Contact: Jeremy Adler